Current Concepts for Genital Herpes Simplex Virus Infection: Diagnostics and Pathogenesis of Genital Tract Shedding
نویسندگان
چکیده
منابع مشابه
Valacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract.
BACKGROUND Valacyclovir exhibits better oral absorption and higher, more prolonged serum concentrations than oral acyclovir. The efficacy of valacyclovir and acyclovir on genital herpes simplex virus (HSV) shedding was assessed in a double-blind, 3-period crossover trial. METHODS Sixty-nine immunocompetent participants with genital HSV-2 received oral valacyclovir, acyclovir, and matching pla...
متن کاملGenital shedding of herpes simplex virus among symptomatic and asymptomatic persons with HSV-2 infection.
CONTEXT Since herpes simplex virus type 2 (HSV-2) antibody tests have become commercially available, an increasing number of persons have learned that they have genital herpes through serologic testing. The course of natural history of HSV-2 in asymptomatic, seropositive persons is uncertain. OBJECTIVE To evaluate the virologic and clinical course of HSV genital shedding among individuals wit...
متن کاملGenital herpes simplex virus infection and gonorrhoea. Association and analogies.
The association of genital herpetic infections with gonorrhoea and other venereal diseases has been noted since the latter part of the 19th century (Diday and Doyon, 1886). Recently, Beilby, Cameron, Catterall, and Davidson (1968) in England have suggested the possibility that gonorrhoeal infection may trigger recurrences of herpetic cervicitis. To test this hypothesis, the present study was co...
متن کاملValacyclovir to reduce transmission of genital herpes simplex virus infection.
fallacy. Am J Epidemiol 1988; 127:893–904. 3. Greenland S, Robins J. Invited commentary: ecologic studies–biases, misconceptions, and counterexamples. Am J Epidemiol 1994; 139: 747–60. 4. Blaser MJ, Chen Y, Reibman J. Does Helicobacter pylori protect against asthma and allergy? Gut 2008; 57:561–7. 5. Höök-Nikanne J, Pérez-Pérez GI, Blaser MJ. Antigenic characterization of Helicobacter pylori st...
متن کاملDNA immunization against experimental genital herpes simplex virus infection.
A nucleic acid vaccine, expressing the gene encoding herpes simplex virus (HSV) type 2 glycoprotein D (gD2) under control of the cytomegalovirus immediate-early gene promoter, was used to immunize guinea pigs against genital HSV-2 infection. The vaccine elicited humoral immune responses comparable to those seen after HSV-2 infection. Immunized animals exhibited protection from primary genital H...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 2016
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.00043-15